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Mariel Kozberg, MD, PhD


Mariel Kozberg, MD, PhD


Massachusetts General Hospital


MGH Research Fellows



For nearly 30 years, the funding provided by the Rappaport Foundation to physicians and researchers has allowed brilliance to flourish and breakthroughs to triumph in the areas of neurologic diseases and mental illness.

Mariel Kozberg is a vascular neurologist at Massachusetts General Hospital and an Instructor of Neurology at Harvard Medical School. Dr. Kozberg received her BS in Chemical-Biological Engineering from the Massachusetts Institute of Technology and completed her MD and PhD (neurobiology) degrees at Columbia University, College of Physicians and Surgeons. For her PhD thesis, she studied the postnatal development of neurovascular coupling, the relationship between neural activity and blood flow in the brain. Remaining focused on the brain’s vasculature, Dr. Kozberg went on to complete a Neurology Residency and Vascular Neurology Fellowship at Mass General Brigham.

Dr. Kozberg’s current research and clinical practice are centered around hemorrhagic stroke. In the lab, she studies cerebral amyloid angiopathy, a common age-related small vessel disease which is a leading cause of symptomatic intracerebral hemorrhage. Using both human tissue and rodent models, she studies the mechanisms through which vascular pathophysiology, blood-brain barrier disruption, and brain inflammation contribute to intracerebral hemorrhage. Clinically, she sees patients who have suffered from both ischemic and hemorrhagic strokes and is establishing an outpatient practice focused on providing care to patients at risk for hemorrhagic stroke, including hemorrhagic stroke survivors. Her research is currently funded through a Heitman Young Investigator Career Development Award and an American Heart Association – Bugher Center for Brain Health in Hemorrhagic Stroke Fellowship.