“As the inaugural Co-Chairs of the Rappaport MGH Grand Challenge Advisory Board, we are grateful to The Phyllis & Jerome Lyle Rappaport Foundation for establishing the Rappaport MGH Grand Challenge Award. This visionary gift is inspiring our investigators to collaborate in new ways and tackle some of the most pressing questions in medicine. The opportunity to support bold, interdisciplinary science with the potential to improve patient care is an extraordinary privilege made possible by the generosity of the Foundation.”